Complexity - Emergent properties of molecules

Principal Investigator: 
Professor Robert C Glen

Complexity - Emergent properties of molecules

Dr. Dmitry Nerukh, previously in the Glen group and now a lecturer in the University of Aston, has been investigating complexity theory applied to protein folding, ECG analysis and photonic devices. The main focus has been on protein dynamics. An EU Framework-6 project led by Dmitry, with seven partners, coordinated in Cambridge, have published over 70 publications (EMBIO http://www-embio.ch.cam.ac.uk/main.html ). Complexity investigations formed the basis of research with George Karvounis (PhD student) and Christian Jensen (PhD student). The goal of the project is to quantify the complexity associated with self-organization in bio-molecular systems as a means to understand complex phenomena in systems that exhibit spontaneous emergence. As a spin-off, we also investigated Electrocardiograms using similar methods with Yuri Chesnekov (Y.C. Chesnokov, D. Nerukh D., R.C. Glen Individually adaptable automatic QT detector. In Proc. Of Computers in Cardiology (2006) pp. 337-340) and were successful in winning the open section of the the Physionet challenge to interpret ECG results:-http://www.physionet.org/challenge/2006/papers/k53-10.pdf .

 

Summary
Date: 
Oct 2003 - Dec 2009